What is it?
Allura Red AC is a man-made dark-red dye made from petroleum-based chemicals. It is an azo dye, one of the Southampton Six colours. In the US it is called Red 40 (FD&C Red No. 40).
also: Allura Red AC · FD&C Red No. 40 · Red 40 · Food Red 17
A synthetic red azo dye made from petroleum, used to colour food and drinks. One of the six colours required by UK law to carry a hyperactivity warning.
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Carbonated Water, Sucrose, Acid (Citric Acid), Flavourings, Acidity Regulator (Sodium Citrates), Preservatives (Potassium Sorbate, Sodium Benzoate), Caffeine (0.025%), Vitamins (B3, B6), Colour (E129)
Linked to more hyperactivity in ordinary children, not only those with ADHD.
UK supermarket foods that declare E129: 88 of the 43,325 we checked (0.2%)
Counted by its code or its name in the ingredient list.
Counted by NutraSafe from UK supermarket ingredient lists, September 2026. How we counted
Why it’s worth knowing. Linked to more hyperactivity in ordinary children, not only those with ADHD. Mouse research suggests eating it all the time may raise serotonin in the gut and make bowel inflammation more likely. Young children who eat a lot of it can go over the daily limit.
Allura Red AC is a man-made dark-red dye made from petroleum-based chemicals. It is an azo dye, one of the Southampton Six colours. In the US it is called Red 40 (FD&C Red No. 40).
It is there only for colour, a bright red to orange-red. It adds no flavour, does not preserve and adds no nutrition. It holds its colour in light, heat and acid, which makes it reliable in factory-made food.
Red sweets, chewing gum, fruit-flavoured drinks and squashes, some sports drinks, flavoured crisps, cereal bars, glacé cherries, jelly, some cakes and biscuits, and some ice creams. It is common in berry, cherry and strawberry fizzy drinks. UK labels call it Allura Red AC or E129.
The 2007 University of Southampton trial, published in The Lancet, gave children aged 3 and 8 to 9 mixtures of six artificial colours, including E129, with the preservative sodium benzoate, or a dummy drink. The children were measurably more hyperactive after the colour mixes. The effect showed up in children in general, not only those already diagnosed with ADHD. Because the trial tested mixtures, it cannot say how much of the effect, if any, came from E129 alone.
Mixtures containing E129 and five other man-made colours, plus sodium benzoate, clearly increased hyperactive behaviour in 3-year-olds and 8 to 9-year-olds from the general population.
Reviewers said the Southampton study gave some evidence of an effect on activity and attention in children, though the design could not separate out single dyes.
A 2022 study from McMaster University in Canada fed mice Allura Red AC over a long period. Their bowels made more serotonin, the lining of the gut let more through, and they were more likely to develop bowel inflammation in a lab model of inflammatory bowel disease. This only happened with constant exposure, not now-and-then exposure. It was a mouse study.
Constant, but not occasional, exposure to Allura Red AC made mice more prone to bowel inflammation, by raising gut serotonin and weakening the gut lining.
A 2024 review in the journal Carcinogenesis said the substances gut bacteria break it into may be able to damage DNA, and called for proper cancer studies.
A review concluded that its effects on inflammation, gut bacteria and DNA-damage pathways make it "suspect and worthy of further molecular investigation". No studies focused on cancer have yet been done.
In 2009 European reviewers found that children aged 1 to 10 who eat a lot of coloured food could go over the daily limit of 7mg per kg of body weight if every food held the legal maximum. So going over the limit matters most for children who have several E129 foods and drinks in a day.
With every food at the legal maximum, estimated intake in children aged 1 to 10 went over the daily limit of 7mg per kg of body weight.
Daily limit. 7mg per kg of body weight a day, about 490mg for a 70kg adult (international committee 1980, confirmed by European reviewers 2009).
Children with noticeable hyperactivity or attention problems may be worth watching, especially if they have several E129 foods and drinks in a day. Parents who want to cut down should check labels for Allura Red AC or E129. Anyone with an inflammatory bowel condition may want to know about the early mouse research. Allura Red is one of the Southampton Six, where the several-a-day question is set out.
The hyperactivity link is the most established concern. It led to a compulsory warning label across the UK and EU, and the 2007 trial behind it was a proper randomised trial, not just an observed pattern. Its limit is that it tested six colours plus a preservative together, so it has not shown that E129 alone causes the effect.
The 2022 gut inflammation findings are striking, but they come from mice fed the dye all the time. The research is still going, and regulators have not restricted it beyond the warning label.
No. E129 is allowed in the UK, but any food or drink containing it must say it "may have an adverse effect on activity and attention in children". The Food Standards Agency asked makers to remove it in 2008, and many did, but it is still legal.
UK and EU law requires any product containing E129 to print "may have an adverse effect on activity and attention in children", followed by the name or E number of the colour. It came into force in July 2010, after the 2007 University of Southampton trial published in The Lancet.
It is approved, with a daily limit of 7mg per kg of body weight and a legal children's behaviour warning. The trial behind the warning found more hyperactivity from a mixture of colours, so E129's own part is not known. Mice fed it constantly were more prone to bowel inflammation.
It is most common in red or orange sweets, fruit-flavoured fizzy drinks and squashes, sports drinks, glacé cherries, jelly, some cereals, flavoured crisps and some biscuits and cakes. Labels call it Allura Red AC or E129.
The dye is made from petroleum-based chemicals and contains nothing from animals, and most vegan organisations treat it as vegan. It was tested on animals for its safety assessment, which some vegans object to.
Last reviewed: 9 November 2026
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