Animal feed safety evaluation
EFSA evaluated ammonium formate as a feed additive in 2020 and concluded it was of low concern for target animal species at the intended use levels. The evaluation was specific to animal feed, not human food use. No human dietary intake assessment was performed because it is not authorised for human food.
EFSA's Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) assessed ammonium formate (E 295) and found it acceptable as a preservative in feed for all animal species at the proposed maximum levels.
2020Regulatory reviewEFSA Journal, Safety of ammonium formate (E 295) for all animal species
Formate and formic acid: basic toxicology
Formate is a normal metabolite produced in the human body in small amounts. At very high doses, formic acid is toxic, causing metabolic acidosis, as seen in methanol poisoning where formate accumulates. At the low levels present in trace dietary exposure, formate is metabolised and excreted. There is no established concern at background dietary exposure levels.
Formic acid and formates occur naturally in many foods including honey, fruits and some fermented products, and are normal metabolites in humans. Toxicity from formate is dose-dependent and associated with high acute exposures, not background dietary levels.
RegulatoryEFSA background documentation on formic acid