E-numbers  /  Thickeners & emulsifiers  /  E472b

Lactic acid esters of mono- and diglycerides

also: Lactem · LACTEM

An emulsifier made from fats and lactic acid. It keeps bread soft, holds whipped cream up and makes spreads smooth. A large French study linked eating more of it to heart disease and stroke.

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An ingredient list from the cakes, biscuits and desserts aisle

Whole Milk · Whipping Cream (Milk) (21%) · Water · Sugar · Dried Skimmed Milk · Invert Sugar Syrup · Instant Coffee (2%) · Cornflour · Beef Gelatine · Emulsifier: E472b · Vanilla Extract.

E472bThickener / Emulsifier

Lactic acid esters of mono- and diglycerides

Lactic acid esters of mono- and diglycerides, also called LACTEM, are made by joining partly broken-down fats to lactic acid, the acid in fermented foods.

220

of the 43,325 UK supermarket foods we checked declare E472b in their ingredients

That is 0.5%, counted by its code or its name.

Only 18% of these labels print “E472b”. Most use the name: look for “lactic acid esters of mono- and diglycerides of fatty acids”.

Counted by NutraSafe from UK supermarket ingredient lists, September 2026. How we counted

How common it is in UK food, by aisle

  • Cakes, biscuits and desserts156 products4.2% of 3,715
  • Bread and bakery33 products0.9% of 3,682
  • Yoghurt, milk and dairy14 products0.6% of 2,273
  • Ice cream and frozen desserts10 products1.3% of 762

What lactic acid esters of mono- and diglycerides is, what it does and where you will see it

What is it?

Lactic acid esters of mono- and diglycerides, also called LACTEM, are made by joining partly broken-down fats to lactic acid, the acid in fermented foods. The fats can come from plants or animals. The result is an emulsifier, which means it stops oil and water separating.

What does it do?

It sits where oil and water meet and keeps them mixed. In bread and cakes it slows staling and improves the crumb. In squirty cream and whipped toppings it holds the air bubbles. In margarine and spreads it gives a smooth, even texture. The lactic acid also adds a little acidity.

Where you will see it

Packaged sliced bread, rolls and cakes, squirty cream, margarine and low-fat spreads, coffee whiteners, and some infant formula. UK labels call it E472b or lactic acid esters of mono- and diglycerides of fatty acids.

What the science says

Linked to heart disease and stroke in a large French study

The NutriNet-Santé study asked about 95,000 French adults to record everything they ate, then followed their health for about 7 years. People who ate more E472b had more heart and circulation disease, and more disease of the blood vessels in the brain, such as stroke. This shows a link, not proof that E472b causes it, and the researchers said the results need repeating in other groups of people.

Among 95,442 French adults followed for a median of 7.4 years, higher intake of lactic acid esters of mono- and diglycerides (E472b) was linked to higher risk of heart and circulation disease and of disease of the blood vessels in the brain.

2023Observational study in peopleSellem et al., BMJ, NutriNet-Santé cohort

The gut breaks it down into everyday parts

In the gut LACTEM is broken down into glycerol, lactic acid and fats. All three are normal parts of food and are used or passed out in the usual ways. Because it breaks down so quickly into everyday substances, it does not build up in the body.

Reviewers concluded E472b is largely broken down in the gut into glycerol, lactic acid and fats, which are normal parts of the diet handled in the usual ways.

2020Regulator reviewEFSA Panel on Food Additives and Flavourings (FAF), EFSA Journal

No long-term studies of it exist

When European reviewers looked at it in 2020, there were no long-term cancer studies or multi-generation reproduction studies of E472b itself. Short and medium-term animal studies showed no harm. They set no numerical daily limit, because what it breaks down into are ordinary food substances and no toxicity was found at permitted levels.

Short and medium-term animal studies showed no harm from E472b. No long-term cancer studies were found. Reviewers noted this as a gap in the data but, given what it breaks down into, did not treat it as a safety issue.

2020Regulator reviewEFSA Panel on Food Additives and Flavourings (FAF), EFSA Journal 18(3):e06032

No numerical daily limit was set, because reviewers found no evidence of harm at permitted levels and it breaks down into normal food substances.

2020Regulator reviewEFSA Panel on Food Additives and Flavourings (FAF), EFSA Journal 18(3):e06032

It may be made from animal fat

The fat in LACTEM usually comes from plant oils such as sunflower or palm, but it can come from animal fat, including pork or beef fat. Unless the label says so, a shopper cannot tell whether a product's E472b is vegan or meets religious rules. UK law does not make makers say where the fat came from.

Mono- and diglyceride esters, LACTEM included, may be made from animal or plant fats, and UK and EU labels do not have to say which beyond the E-number.

LawUK FSA approved-additives guidance; EU Regulation 1333/2008

Where it stands with the regulators

Approved in the UK and the EU

Daily limit. None set (European reviewers, 2020).

Legal basis
On the Food Standards Agency's approved list for Great Britain
Permitted foods
Bread, cakes and pastries · Margarine and spreads · Squirty cream · Coffee whiteners and creamers · Infant and follow-on formula, within set limits · Cereal foods for infants and young children · Chewing gum · Ices · Processed cheese
Maximum levels
No set maximum in most foods, as long as makers use no more than they need. Foods for infants and young children have set limits.
History
On the EU's first list of approved additives. European reviewers looked at it again in 2020, with the rest of the E472 family (E472a to f), raised no safety issue at permitted levels and set no numerical daily limit. In 2023 a large French study linked higher intake to heart disease and stroke, which regulators have not yet assessed.

Who should be careful

Vegans, vegetarians and anyone keeping halal or kosher should know E472b may be made from animal fat. The label will say E472b or lactic acid esters of mono- and diglycerides of fatty acids, but not where the fat came from. Ask the maker if it matters to you.

The honest read

E472b is one of a large family of emulsifiers made from fats, used in food for decades. The 2020 European review found nothing in the toxicity data to raise a concern at the amounts used, and set no daily limit because it breaks straight down into things the body already handles. There are, though, no long-term studies of E472b itself.

The newer question is the French NutriNet-Santé research, which linked higher intake to heart disease and stroke. That is one large study and shows a link, not proof. The everyday issue for many shoppers is simpler: the fat source is not on the label, which matters for vegans and religious diets.

Common questions about lactic acid esters of mono- and diglycerides

Is E472b banned in the UK?

No. E472b is allowed in the UK and is on the Food Standards Agency's approved list.

Is E472b linked to heart disease?

A French study of 95,442 adults, published in 2023, found people who ate more E472b had more heart and circulation disease and more stroke-type disease. It is one observational study and shows a link, not proof that E472b causes it.

Is E472b vegan?

Not necessarily. The fats used to make it can come from plant oils or animal fats such as lard or tallow. UK law does not make makers say which, so you cannot tell from the label. Ask the maker if you need to be sure.

What foods contain E472b?

Mostly packaged sliced bread and rolls, cakes, squirty cream, margarine and low-fat spreads, coffee whiteners and some infant formula.

Does E472b build up in the body?

No. The gut breaks it down into glycerol, lactic acid and fats, all ordinary parts of food that the body uses or passes out.

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