E-number field guide

Flavour enhancers, properly explained.

A researched guide to what this category means on a UK label, the important subtypes, and all 20 entries in NutraSafe’s published library.

Example UK ingredients-list format

Flavour enhancer: E621

Monosodium glutamate
20library entries
3key distinctions
4primary sources
The plain-English answer

What flavour enhancers actually do

Flavour enhancers strengthen or round out tastes already present in a food. They are different from flavourings, which add a flavour of their own, although the distinction is easy to miss in a long ingredients list.

This directory covers the flavour-enhancer records in our published database. Each code links to a full page with its own research, regulatory notes and source list.

Know the differences

One category. Several very different jobs.

The exact code matters more than the category headline. These are the distinctions that make the list easier to read without turning every additive into the same story.

03

Function is not the same as flavour

A flavour enhancer strengthens taste or odour already present; a flavouring adds or modifies flavour. That distinction explains why a label may use one term rather than the other.

A better way to read the packet

Function first, then the exact name

1

Find the function

UK guidance says the ingredients list identifies what the additive does, such as “preservative” or “antioxidant”.

2

Read the name or E-number

The specific substance can follow as a name or code. Both routes identify the additive; neither is a safety score.

3

Open the individual entry

That is where NutraSafe separates source, uses, current regulatory detail, research notes and citations for that code.

Current GB context: since 1 April 2025, the FSA’s electronic register has been the official public list of authorised food additives in Great Britain. An authorisation can include food-category limits and notes, so appearing in a directory does not mean unrestricted use in every food. Read the register guidance.

All flavour enhancers

Showing all 20

Browse the complete E-number A to Z

Glutamate activates umami taste receptors on the tongue (the T1R1/T1R3 receptor complex and metabotropic glutamate receptors), producing the savoury, mouth-filling quality described as umami, the fifth basic taste alongside sweet, sour, salty and bitter.

Read the full entry

GMP binds to umami taste receptors on the tongue and dramatically amplifies the savoury signal, particularly when combined with glutamates such as monosodium glutamate (E621).

Read the full entry

GMP is a nucleotide that binds to umami taste receptors (the T1R1/T1R3 heterodimer on the tongue) and dramatically amplifies the umami signal produced by glutamates such as monosodium glutamate (MSG, E621).

Read the full entry

Guanylates bind to umami taste receptors on the tongue and dramatically amplify the perceived savoury intensity of food, particularly when combined with glutamates such as E621 (MSG).

Read the full entry

As a flavour enhancer, L-leucine contributes a mildly bitter taste characteristic that can round out or intensify savoury profiles in combination with other flavour compounds.

Read the full entry
Questions, answered

What people usually want to know

Is a flavour enhancer the same as a flavouring?

No. The legal class covers substances that enhance an existing taste or odour. Flavourings are regulated separately and are used to give or modify flavour.

Is MSG the only flavour enhancer?

No. MSG is E621, but the directory also includes other glutamates, guanylates, inosinates and combined ribonucleotides.

Why do some products use more than one enhancer?

Different enhancers can be used together for a particular recipe effect. The ingredients list should identify each additive used.

How this guide was checked

Primary sources, not filler

The category explanation and label rules above were checked against official UK guidance, the GB authorisations register, legislation and EFSA background material. Individual additive pages carry the sources for their additive-specific claims.

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Directory updated: 16 September 2026
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