EFSA 2017 re-evaluation: no numerical ADI needed
The European Food Safety Authority reviewed E1422 and eleven other modified starches in 2017. Its conclusion was that modified starches as a group posed no safety concern at the levels found in food, and that no numerical acceptable daily intake needed to be set. The panel noted that modified starches are digested in the same way as ordinary starch, producing glucose as the main breakdown product, and that the chemical groups added during modification (acetyl and adipate) are present at very low levels in the food as consumed.
EFSA concluded there was no safety concern for the use of acetylated distarch adipate (E1422) and related modified starches as food additives at reported use levels in the general population, and that no numerical ADI was necessary.
2017Regulatory reviewEFSA Panel on Food Additives and Nutrient Sources (ANS), EFSA Journal
Digestibility and infant use
Modified starches including E1422 are broken down by digestive enzymes in the same way as native starch, primarily to glucose. The cross-linking modifications do not survive digestion intact. E1422 is specifically permitted in processed cereal-based foods and baby foods under EU and UK rules, and was considered acceptable for infant use by EFSA in the 2017 review at the levels then in use. Because infants are smaller, their per-kilogram exposure to any ingredient from food is proportionally higher than adults, but the review found no concern at reported use levels.
Modified starches listed in Annex II of EU Regulation 1333/2008, including E1422, are permitted in processed cereal-based foods and baby foods for infants and young children at quantum satis (as needed) or specified limits, subject to the conditions of Directive 2006/52/EC.
RegulatoryEU Regulation 1333/2008 Annex II, assimilated into UK law
EFSA's 2017 re-evaluation included infant dietary exposure modelling and found no safety concern for modified starches including E1422 in processed foods for infants and young children at reported use levels.
2017Regulatory reviewEFSA Panel on Food Additives and Nutrient Sources (ANS), EFSA Journal