Magnesium as an essential nutrient
Magnesium is an essential mineral required for hundreds of enzymatic reactions, including energy production, protein synthesis, nerve and muscle function, and bone formation. The UK Reference Nutrient Intake is 300mg per day for adult men and 270mg per day for adult women. The small amounts contributed by E511 as a food additive count toward total dietary magnesium intake, which most UK adults consume at adequate but not excessive levels.
Magnesium is an essential cofactor for over 300 enzymatic reactions and is required for DNA synthesis, protein synthesis, and normal muscle and nerve function.
EstablishedSACN (Scientific Advisory Committee on Nutrition), UK
The UK Reference Nutrient Intake for magnesium is 300mg per day for men and 270mg per day for women aged 19 and over.
1991RegulatoryUK Department of Health, Dietary Reference Values for Food Energy and Nutrients
Excess magnesium intake: laxative effect at high doses
At high supplemental doses, magnesium salts including magnesium chloride can cause osmotic diarrhoea because unabsorbed magnesium ions draw water into the intestine. This effect is well documented for magnesium supplements but the amounts present in food as E511 are far below the doses associated with this effect. The European Food Safety Authority set an upper tolerable intake level of 250mg per day for supplemental magnesium specifically to avoid this laxative threshold.
Supplemental magnesium at doses above 250mg per day is associated with diarrhoea due to osmotic effects in the gut; this is the basis for EFSA's tolerable upper intake level for supplemental magnesium.
2015Regulatory reviewEFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Scientific Opinion on Dietary Reference Values for Magnesium