Sulphite release from the bisulphate sub-form
Potassium hydrogen sulphate (E515ii) releases sulphite species when dissolved in water. Sulphites are established triggers for asthma and hypersensitivity reactions in sensitive individuals, including wheezing, chest tightness, and anaphylaxis in severe cases. This is why sulphites above 10 parts per million must be declared on UK food labels. E515i (the neutral sulphate) does not generate sulphite in the same way.
Sulphites are recognised as a cause of asthma exacerbations and allergic-type reactions in sensitive individuals, with the response being more pronounced in people with underlying asthma.
2016Regulatory reviewEFSA Panel on Food Additives and Nutrient Sources (ANS), EFSA Journal
UK food labelling law requires declaration of sulphites and sulphur dioxide when present above 10mg/kg in the final food, reflecting the established hypersensitivity risk.
2014RegulatoryUK Food Information Regulations 2014 and assimilated EU Regulation 1169/2011, Annex II
Potassium load and kidney considerations
Both sub-forms contribute potassium to the diet. At typical food additive use levels this is nutritionally trivial for healthy people. For individuals with impaired kidney function, however, excess potassium from all dietary sources, including additives, can accumulate and contribute to hyperkalaemia, a raised blood potassium level that affects heart rhythm. No specific concern at normal food use levels has been established by regulators for the general population.
People with chronic kidney disease are advised by clinical guidelines to monitor total potassium intake from all food sources, including potassium-containing additives.
RegulatoryBritish Dietetic Association, Kidney Disease Dietary Guidelines