Dietary aluminium and neurological concern
The body of concern around aluminium silicates as food additives centres on total dietary aluminium intake rather than this specific compound in isolation. EFSA set a tolerable weekly intake across all dietary aluminium sources. Studies in animals show aluminium accumulates in bone and brain tissue and can cause neurotoxic effects at sustained high doses. Human epidemiological evidence linking dietary aluminium to neurological conditions remains observational and contested.
EFSA established a tolerable weekly intake of 1 mg aluminium per kg body weight per week, based on neurotoxicity and reproductive effects in animal studies, concluding that dietary exposure from all aluminium-containing food additives combined could approach or exceed this limit.
2008Regulatory reviewEFSA AFC Panel, Scientific Opinion on the safety of aluminium from dietary intake
A subsequent EFSA re-evaluation of the remaining authorised aluminium silicate additives (E554, E555) found that combined aluminium intake from food additives alone could, in some population groups, approach the tolerable weekly intake, contributing to decisions to restrict or remove some aluminium-based additives.
2020Regulatory reviewEFSA ANS Panel, Re-evaluation of sodium aluminium silicate (E554) and potassium aluminium silicate (E555) as food additives, EFSA Journal
In laboratory and animal studies, aluminium exposure at high sustained doses causes accumulation in bone matrix, liver and brain tissue, with neurobehavioural effects observed in rodent models at doses above the TWI.
2020Lab + animalEFSA ANS Panel, EFSA Journal
Revocation: why E559 is no longer authorised
E559 was included in EU Regulation 1333/2008 Annex II with a transitional period expiring on 31 January 2014. The European Commission did not renew the authorisation. The UK FSA records E559 as revoked from this date. Foods lawfully placed on the market before that date could be sold until stocks ran out, but no new production using E559 has been permitted since.
The UK Food Standards Agency database lists E559 (Aluminium silicate, Kaolin) with status 'Revoked', noting that 'the period of application expired on 31 January 2014'.
2014RegulatoryUK Food Standards Agency, Authorised Regulated Food and Feed Products Register, E559 entry