The body handles it like glucose
Once it turns into gluconic acid in the body, it is used through the same routes as glucose. Gluconic acid is in fruit and honey, and the body makes it too. Reviews have found no harm to organs, no cancer, no DNA damage and no effects on reproduction at the amounts in food. The WHO's cancer agency has not classified it.
Repeated-dose animal studies at doses well above anything food could supply found no harm, and standard tests found no DNA damage.
Regulator reviewEFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), re-evaluation programme for E574-E579
Gluconic acid and its salts are used by the body through normal carbohydrate routes, and the body also makes gluconic acid from glucose.
Regulator reviewJoint FAO/WHO Expert Committee on Food Additives (JECFA)
European reviewers have not finished their review
Every additive approved in the EU before January 2009 is being reviewed again. E575 is in the group for gluconic acid and related salts, E574 to E579. By 2024 reviewers had asked for data on this group, so their formal conclusion had not been published. No early warning has been announced.
European reviewers asked for data on gluconic acid (E574) and related additives including E575 to E579, as part of re-checking older additives.
2024Regulator actionEFSA Call for Data on re-evaluation of E574-E579