Where tartrate comes from in the diet
Tartaric acid and its salts occur naturally in grapes, wine, tamarinds and bananas. The body absorbs only a small fraction; most passes through unchanged to be broken down by gut bacteria or excreted. This means dietary exposure from the additive is a small addition to a background that already comes from everyday fruit and wine consumption.
Tartaric acid and tartrate salts (E334-337, E354) are metabolised partly by intestinal bacteria and partly excreted; absorbed amounts are low and no accumulation in tissues has been identified at food-use levels.
2020Regulatory reviewEFSA Panel on Food Additives and Nutrient Sources (ANS), re-evaluation of tartaric acid and its salts (E334-337, E354), EFSA Journal
Regulatory safety conclusion
EFSA completed a full re-evaluation of the tartrate group (which includes E337) in 2020 as part of its systematic review of all approved EU food additives. The panel found no toxicological concern at the levels used in food and did not set a numerical acceptable daily intake, judging the existing approvals to be sound.
EFSA concluded that tartaric acid and its salts, including sodium potassium tartrate (E337), raised no safety concern at current permitted and estimated dietary exposure levels, and no numerical ADI was considered necessary.
2020Regulatory reviewEFSA Panel on Food Additives and Nutrient Sources (ANS), EFSA Journal 2020;18(3):e06030
Laxative effect at high doses
In large amounts, tartrate salts can have a laxative effect because unabsorbed tartrate draws water into the colon. This is a well-documented property that was once exploited medicinally. At the levels present in food it is not a practical concern, but products eaten in quantity, such as certain baking powders, could contribute meaningfully to intake.
High oral doses of tartrate salts produce osmotic laxative effects in humans; the threshold is well above realistic dietary exposure from approved food uses.
2020Regulatory reviewEFSA Panel on Food Additives and Nutrient Sources (ANS), re-evaluation of tartaric acid and its salts (E334-337, E354), EFSA Journal